BioMeca is able to quantify the blinding strength of tris-Ni+-NTA groups to histidine residues and validate the number of TransMembrane Domains (TMD) in this protein receptor.
Light on our solutions
How to characterize a proteoliposome in solution ?
To characterize a transmembrane protein by High Resolution Imaging and localize its binding sites, BioMeca® provides 2 solutions :
- Force-Distance curve-based Atomic Force Microscopy (FD-based AFM) technology for High Resolution Imaging,
- AFM tips functionalization with a tris-Ni+-NTA groups, to detect the specific protein binding sites, at the nanometer resolution.
Need more innovative pharmacologic solutions?