How to characterize transmembrane proteins?

To characterize a transmembrane protein by High Resolution Imaging and localize its binding sites, BioMeca® provides 2 solutions.


BioMeca®’s solutions

BioMeca® quantifies the blinding strength of tris-Ni+-NTA groups to histidine residues and validates the number of TransMembrane Domains (TMD).

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Case studies


Spheroids as microtissues are a powerful alternative to standard 2D cell culture for in vitro studies. 3D scaffold-free spheroids are formed within a few days from a cell suspension using hanging drop technology.
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Case studies

Skin disorders

The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. Several damages in stratum corneum involve skin barrier disorders as Atopic Dermatitis, complex disease due to multiple factors (immunologic, genetic, environnemental).
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Case studies

Tissue stiffness

Pancreatic cancer is the 4th most frequent cause of cancer-related deaths worldwide and should become the 2nd one hence 2030. The extracellular matrix in the tumor microenvironment modulates the cancer cell phenotype and need to be more studied to develop efficient treatment
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