How to characterize the biomechanical and structural properties of a spheroid?

Spheroids as microtissues are a powerful alternative to standard 2D cell culture for in vitro studies. 

 

BioMeca®’s solutions

BioMeca® measures the density of elastic fibres and biomechanical properties of the microdermis, and quantifies the correlation between elastic modulus maps and density of elastin deposits.

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Binding proteins characterization

To characterize a transmembrane protein by High Resolution Imaging and localize its binding sites, BioMeca® provides 2 solutions.
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Case studies

Skin disorders

The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. Several damages in stratum corneum involve skin barrier disorders as Atopic Dermatitis, complex disease due to multiple factors (immunologic, genetic, environnemental).
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Case studies

Tumor escape and extracellular matrix

A new dependence receptors family (DR) has been discovered by one of our academic partner. These receptors inhibit tumor progression by inducing apoptosis when cancer cells are in absence of DR ligands.
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