How to mechanically characterize the extracellular matrix synthesized by lung cancer cells ?

A new dependence receptors family (DR) has been discovered by one of our academic partner. These receptors inhibit tumour progression by inducing apoptosis when cancer cells are in absence of DR ligands.


BioMeca®’s solutions

BioMeca® studies mechanical structure and morphometry of ExtraCellular Matrix (ECM) synthetized by cancer cells and investigate specific cancer cells whose express a putative protein tumour suppressors controlling cell death commitment.

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Case studies

Tissue stiffness

Pancreatic cancer is the 4th most frequent cause of cancer-related deaths worldwide and should become the 2nd one hence 2030. The extracellular matrix in the tumor microenvironment modulates the cancer cell phenotype and need to be more studied to develop efficient treatment
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Case studies

Skin disorders

The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. Several damages in stratum corneum involve skin barrier disorders as Atopic Dermatitis, complex disease due to multiple factors (immunologic, genetic, environnemental).
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Case studies

Binding proteins characterization

To characterize a transmembrane protein by High Resolution Imaging and localize its binding sites, BioMeca® provides 2 solutions.
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