Light on our solutions

Case studies

Tumor escape and extracellular matrix

A new dependence receptors family (DR) has been discovered by one of our academic partner. These receptors inhibit tumor progression by inducing apoptosis when cancer cells are in absence of DR ligands. Due to the frequent inactivation of their apoptotic function in human…
See the study
Case studies

Skin disorders

The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. Several damages in stratum corneum involve skin barrier disorders as Atopic Dermatitis, compex disease due to multiple factors (immunologic, genetic, environnemental)…
See the study
Case studies

Characterization of a proteoliposome

To characterize a transmembrane protein by High Resolution Imaging and localize its binding sites, BioMeca® provides 2 solutions : Force-Distance curve-based Atomic Force Microscopy (FD-based AFM) technology for High Resolution Imaging, aAFM tips functionalization with a…
See the study
Case studies

Tissue stiffness

Pancreatic ductal adenocarcinoma (PDAC) is the fourth most frequent cause of cancer-related deaths worldwide and should become the second one hence 2030. The extracellular matrix (ECM) in the tumor microenvironment modulates the cancer cell phenotype, especially in…
See the study
Case studies

Spheroids

Spheroids as microtissues are a powerful alternative to standard 2D cell culture for in vitro studies. 3D scaffold-free spheroids are formed within a few days from a cell suspension using hanging drop technology. The advantages of spheroids exclusively composed of …
See the study