How to reveal a plumping effect through skin mechanical properties ?

Should skin pumpling a synonym to collagen production ? Yes certainly but not only. Stimulating microcirculation, moisturizing, nourishing are also effects to promote.

DermoMeca®’s solutions

DermoMeca® provides solutions both revealing collagen production, through fibers characterization and quantification, and highlighting moisturizing effect through visco-elasticity studies.

Here, DermoMeca® proposes to study a product’s plumping effect on tissue homeostasis in structural and mechanical terms (qualitative and quantitative study) with AFM.

Biological models : skin explants treated in topic according a time routine

Readouts : 

  • Force-volume curves acquisition
  • Mechanical properties quantification from force curves analyses
  • Skin explant 3D reconstruction from tomographic data
  • Viscoelasticity measurements and analysis

A : Increase of tissue stiffness after treatment

B : Viscoelasticity increase



This solution allows us to claim a plumping effect along different approaches in revealing a significant increase of :

  • tension between epidermis and dermis
  • moisturizing effect of the tested product

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