How to reveal a plumping effect through skin mechanical properties ?

Should skin pumpling a synonym to collagen production ? Yes certainly but not only. Stimulating microcirculation, moisturizing, nourishing are also effects to promote.

DermoMeca®’s solutions

DermoMeca® provides solutions both revealing collagen production, through fibers characterization and quantification, and highlighting moisturizing effect through visco-elasticity studies.

Here, DermoMeca® proposes to study a product’s plumping effect on tissue homeostasis in structural and mechanical terms (qualitative and quantitative study) with AFM.

Biological models : skin explants treated in topic according a time routine

Readouts : 

  • Force-volume curves acquisition
  • Mechanical properties quantification from force curves analyses
  • Skin explant 3D reconstruction from tomographic data
  • Viscoelasticity measurements and analysis

A : Increase of tissue stiffness after treatment

B : Viscoelasticity increase

 

CONCLUSION

This solution allows us to claim a plumping effect along different approaches in revealing a significant increase of :

  • tension between epidermis and dermis
  • moisturizing effect of the tested product
Tool choice
Need more innovative cosmetical solutions ?

Discover our other solutions

Case studies

Tensing effect

The dermis is largely composed of dense collagen-rich extracellular matrix (ECM). Dermal collagen represents by far the most abundant ECM protein and constitutes the bulk of skin. Dermal connective tissue collagen is essentially responsible for the skin’s tensile strength…
See the study
Case studies

Smoothing effect

Skin mobilization is the result of the different mobility capacities of the skin and its underlying structures. When the skin is stretched and mobilized, there is an elastic restoring force opposite to the axis of tension, which tends to return the skin to its previous…
See the study
Case studies

Slimming effect

A slimming cream might have several actions depending on its target. It can regulate and balance storage and removal of fat. In this context, studying adipocytes, the responsible cells for fat storage in adipoe tissue, sheds light on its action’s mode…
See the study