Light on our solutions

Case studies

Plumping effect

Should skin pumpling a synonym to collagen production ? Yes certainly but not only. Stimulating microcirculation, moisturizing, nourishing are also effects to promote.
See the study
Case studies

Hair protection

Hair is a constant victim of many agressions : water, sun, brushing, pollution, having shine and smooth hair with blow dryers and heating irons… The robust structure of its external layer, the cuticle, protects it. But as fantastic is this cuticle, we need to care of it…
See the study
Case studies

Slimming effect

A slimming cream might have several actions depending on its target. It can regulate and balance storage and removal of fat. In this context, studying adipocytes, the responsible cells for fat storage in adipoe tissue, sheds light on its action’s mode…
See the study
Case studies

Smoothing effect

Skin mobilization is the result of the different mobility capacities of the skin and its underlying structures. When the skin is stretched and mobilized, there is an elastic restoring force opposite to the axis of tension, which tends to return the skin to its previous…
See the study
Case studies

Tumor escape and extracellular matrix

A new dependence receptors family (DR) has been discovered by one of our academic partner. These receptors inhibit tumor progression by inducing apoptosis when cancer cells are in absence of DR ligands. Due to the frequent inactivation of their apoptotic function in human…
See the study
Case studies

Skin disorders

The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. Several damages in stratum corneum involve skin barrier disorders as Atopic Dermatitis, compex disease due to multiple factors (immunologic, genetic, environnemental)…
See the study
Case studies

Characterization of a proteoliposome

To characterize a transmembrane protein by High Resolution Imaging and localize its binding sites, BioMeca® provides 2 solutions : Force-Distance curve-based Atomic Force Microscopy (FD-based AFM) technology for High Resolution Imaging, aAFM tips functionalization with a…
See the study
Case studies

Wound healing

Wound healing is a very complex process, specific to every organism and tissue, and addresses several factors and different cellular and tissular groups. Cutaneous wound healing involves many processes of dermis and epidermis regeneration for which physical forces play a…
See the study
Case studies

Tissue stiffness

Pancreatic ductal adenocarcinoma (PDAC) is the fourth most frequent cause of cancer-related deaths worldwide and should become the second one hence 2030. The extracellular matrix (ECM) in the tumor microenvironment modulates the cancer cell phenotype, especially in…
See the study
Case studies

Blue light protection

Light is necessary for life, but long exposure to artificial light is becoming a major health concern. Humans are exposed to increased amounts of light in the blue spectrum produced by light-emitting diodes (LEDs) found in screens and smartphones which can interfere with…
See the study
Case studies

Skin barrier

Epidermal differenciation triggers to the formation of apoptotic cells, corenocytes more or less cohesive. One of the main role of these cells is to regulate epidermis permeability. The skin barrier is due to the accumulation of lipids (free fatty acids, cholesterol, …
See the study
Case studies

Tensing effect

The dermis is largely composed of dense collagen-rich extracellular matrix (ECM). Dermal collagen represents by far the most abundant ECM protein and constitutes the bulk of skin. Dermal connective tissue collagen is essentially responsible for the skin’s tensile strength…
See the study
Case studies

Spheroids

Spheroids as microtissues are a powerful alternative to standard 2D cell culture for in vitro studies. 3D scaffold-free spheroids are formed within a few days from a cell suspension using hanging drop technology. The advantages of spheroids exclusively composed of …
See the study